Fast Stereolithography Printing of Large-Scale Biocompatible Hydrogels
Prof. Ruogang Zhao
Dept. of Biomedical Engineering,
University at Buffalo, SUNY
Wednesday, August 25, Webinar at 6:00 PM Pacific time
Large size cell-laden hydrogel models hold great promise for tissue repair and organ transplantation, but their fabrication using 3D bioprinting is limited by the slow printing speed that can affect the part quality and the biological activity of the encapsulated cells. Here we present a Fast hydrogeL stereOlithogrAphy prinTing (FLOAT) method that allows the creation of a centimeter-sized, multiscale solid hydrogel model within minutes. Through precisely controlling the photopolymerization condition, we establish low suction force-driven, high-velocity flow of the hydrogel prepolymer that supports the continuous replenishment of the prepolymer solution below the curing part and the nonstop part growth. The rapid printing of centimeter-sized hydrogel models using FLOAT was shown to significantly reduce the part deformation and cellular injury caused by the prolonged exposure to the environmental stresses in conventional 3D printing methods. Embeded vessel networks fabricated through multiscale printing allow media perfusion needed to maintain the high cellular viability and metabolic functions in the deep core of the large-sized models. The endothelialization of this vessel network allows the establishment of barrier functions. Together, these studies demonstrate a rapid 3D hydrogel printing method and represent a first step towards the fabrication of large-sized engineered tissue models.
Dr. Ruogang Zhao is an Associate Professor in the Department of Biomedical Engineering at the State University of New York at Buffalo. He received both of his B.Eng. and M.A.Sc. in engineering mechanics and his PhD in biomaterials and biomedical engineering from the University of Toronto. He was a postdoctoral fellow in biological physics at the Johns Hopkins University before moving to Buffalo. Through combining advanced biofabrication technologies and biomechanics, he has developed a unique research program to address the unmet need to model the physiology and pathology of mechanosensitive tissues. During his Ph.D. training, he received the prestigious Heart and Stroke Foundation of Canada Doctoral Research Award. He also received the 2019 Young Innovators Award of Cellular and Molecular Bioengineering from the Biomedical Engineering Society and Outstanding Abstract Award from the Society of Biomaterials in 2019.
EVENT DATE: Wednesday, August 25
Registration deadline: Monday, August 23, 1:00 PM.
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Presented by Prof. Timothy Long, Arizona State University; Prof. David A. Dillard, Virginia Tech; Prof. Mike Bortner, Virginia Tech; Dr. Giles Dillingham, BTG Labs
3-Day Live Virtual Short Course,
October 26, 27 and 29, 2021 (Tuesday, Wednesday, and Friday)
Sponsored by the Golden Gate Polymer Forum.
This 3-day virtual course will address the fundamentals and applications of adhesion science to solve practical adhesive design and bonding challenges. The course will be taught by a well-coordinated team of highly experienced instructors, and will focus on four fundamental perspectives: adhesive structure-property relationships (Long), surface functionalization and characterization (Dillingham), polymer rheology and processing (Bortner), and design and mechanics of adhesive bonds (Dillard). The course will allow participants to gain a broad perspective of the rapidly evolving field of adhesion science and engineering for emerging technologies from electronics to biomedical sciences.
All topics will be presented with an application/use-inspired approach to foster learning, including by those with limited directly relevant technical education or experience. Attendees can expect to learn about surfaces and interfaces, polymer structure-property relationships relevant to adhesives, and the stresses and failure of adhesive joints. Building on these fundamental insights, participants will gain many practical insights into surface preparation, time-dependent adhesive characterization, test method selection, surface and failure analysis, joint design, and adhesive durability. (See detailed topics list in course outline below.)
This course offers an exceptional opportunity with a unique combination of four very experienced researchers/teachers from renowned polymer and adhesion science research programs across the nation, a virtual format to allow broad participation, an affordable price, and a focus on practical applications. Q&A sessions will be incorporated throughout each day.
Who should attend:
Any scientist, engineer or technician who works with bonding, joining, or adhesion issues, including those using polymeric adhesives or sealants, and their use in a research, development, product design, manufacturing, quality control, or reliability context.
Managers in polymer and manufacturing industries will greatly benefit from this broad-based introduction to adhesion issues and opportunities in the field.
The course is structured for those with some scientific or engineering background and those with industrial experience in technology who would like to learn the basics and fundamentals of adhesion science and applications to practical adhesive bonding and engineering challenges.
Dr. Timothy Long holds a joint faculty position in the School of Molecular Sciences and the School for Engineering, Matter, Transport and Energy at Arizona State University. Prof. Long leads the Biodesign Center for Sustainable Macromolecular Materials and Manufacturing within the Biodesign Institute at ASU. His interdisciplinary research group tackles diverse research areas related to the structure-property-processing relationships of polymers with emphasis on sustainable chemistry and engineering, discovery of novel synthetic methods, advanced physical characterization tools, and designing materials with proper reactivity and rheology for additive manufacturing processes. His research has led to over 50 patents and 350 peer-reviewed publications in diverse areas of macromolecular science and engineering. His distinctions include Virginia 2019 Outstanding Faculty Award, American Chemical Society (ACS) PMSE Cooperative Research Award, ACS Division of Polymer ChemistryPOLY Mark Scholar Award, and ACS Fellow (2009).
Dr. David A. Dillard is the Adhesive and Sealant Science Professor in the Biomedical Engineering Science and Mechanics Department at Virginia Tech. He has worked extensively in the field of adhesive bonding, having experience in structural adhesives for aerospace, automotive, and infrastructure applications; adhesives and coatings for microelectronic applications; pressure sensitive adhesives; elastomeric adhesives and sealants, and polymeric membranes, sealants and adhesion issues in alternative energy systems. He has coauthored over 200 publications in refereed journals and regularly teaches courses in adhesion science and viscoelasticity. His research activities focus on developing test methods and predictive models for understanding and estimating the performance and durability of adhesives and bonded joints, using the principles of fracture mechanics and viscoelasticity. He is a Robert L. Patrick Fellow and former President of the Adhesion Society
Dr. Michael J. Bortner is an Associate Professor of Chemical Engineering who specializes in structure-process-property relationships of polymer composite and nanocomposite materials for applications including smart materials and electronics, structural composites, next generation extrusion based additive manufacturing materials, and packaging materials. He implements advanced processing and characterization techniques coupled with numerical modeling to fundamentally understand the interrelationships between intrinsic chemistry-controlled properties, processing technique, and resulting morphology/structure-property relationships. He has over 50 peer reviewed journal manuscripts and conference papers and proceedings, and was recently elected Treasurer of the American Chemical Society Cellulose and Renewable Materials (ACS CELL) Division. He has served as the Chair of the Structural Division of the Adhesion Society and is currently co-chair of the Adhesion Society Annual Meeting.
Dr. Giles Dillingham has worked in the areas of materials, surfaces, interfaces, and adhesive bonding since receiving his Ph.D. in Materials Science in 1987. BTG Labs, established by Dr. Dillingham in the late 1990’s, performs basic and applied research in surface science, surface treatments, and adhesion, and also develops and manufactures instrumentation for the control of surface engineering processes. Recent work by BTG Labs is helping pave the way to certifiable adhesively bonded primary aircraft structures. Dr. Dillingham has over 40 publications and patents in the areas of surface treatments, surface energetics, and adhesion. He is proud to have been elected a Robert A. Patrick Fellow of The Adhesion Society.
Do not reply to this email. See below for contact information.
Class size will be larger than typical in-person events, but GGPF reserves the option to close registration if the size gets too large in our opinion.
Registration deadline dates are tiered, with early, regular, and late registration fees.
Overall Course Schedule
Tuesday, Oct. 26 – Introduction to Adhesion Science
7:30 AM – 6:00 PM Pacific time
Wednesday, Oct. 27 – Adhesion Structure and Characterization
8:00 AM – 6:00 PM Pacific time
Friday, Oct. 29 – Adhesive Processing and Durability
8:00 AM – 5:30 PM Pacific time
Detailed Topics Schedule
(possible slight changes in timing)
Day 1: October 26 - Introduction to Adhesion Science
· Polymeric Adhesive Design: Introduction to Terminology (Long1)
· Water-borne and Photoreactive Systems: Sustainability (Long4)
· Rheological Impact of Additives and Chemorheology of Network Forming Polymers (Bortner5)
· Process Control for Adhesion (Dillingham4)
EVENT DATES: October 26, 27 and 29 (Tuesday, Wednesday, and Friday)
Class materials will be presented using Zoom. Registrants will receive webinar information shortly before the class begins.
Pricing and Deadlines:
$400 early registration, ending Friday, July 16, 5 PM Pacific time.
$500 regular registration, till Monday, October 4, 5 PM Pacific time.
$600 late registration, if still available, until Tuesday, October 19, 5 PM Pacific time.
No registration is complete until payment is received.
No registrations allowed after 5 PM Oct 19 or if class size reaches a practical limit.
Additional instructions will be provided to those who register for the event.
(1) Begin the registration process by completing the required information below, then click "Submit" at the bottom of the page. This will take you to a new page where you can review your information, then click "Confirm Registration". If someone other than the attendee is filling out the registration form, please ensure that it is the attendee's name and contact information in the appropriate fields in the registration. Registrations may only be processed for one attendee at a time.
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Click on the "PayPal" icon. This will redirect you to the PayPal website where you can submit your credit card information and complete the payment process. A PayPal account is not necessary. If you do not have a PayPal account, or if you do not wish to use one which you may already have, do not use the "login" option at the PayPal website; select "Pay with Debit or Credit Card" instead. You can enter your own card info and pay by that directly.
If you must choose to pay by check, you will need to provide payment by mailing a check made out to “GGPF” in the appropriate amount. Contact Jennifer Hoffman for further instructions at JenniferHoffman@eurofinsEAG.com. Your registration will not be considered complete until a check is received.
(3) If your company requires it, the GGPF Tax ID number will be provided to you by e-mailing a request to Jennifer Hoffman. Please note that the conference registration fee covers the short course expenses and is not a tax deductible donation.
(4) An automated e-mail receipt will be provided as soon as you register and is usually sufficient for corporate reimbursement. If you require a hardcopy receipt, please contact us (via Jennifer Hoffman) and one can be mailed to you.
No cancellations allowed after Oct. 19.
You must cancel in writing or e-mail and have a verifiable acknowledgment from us that you have cancelled in time.
Cancellations on or before Oct. 19 deadline will result in a refund, minus a $50 cancellation fee.
If you must cancel, another member of your company/organization may be substituted without cancellation fee, by special arrangement; contact GGPF.
If for any reason GGPF must cancel the course (not anticipated), you will be notified and a full refund will be given to all registrants.
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For questions about registration, payment, cancellations, or web page problems -
Jennifer Hoffman, JenniferHoffman@eurofinsEAG.com
The Golden Gate Polymer Forum (GGPF) is a successful 40-year non-profit educational organization dedicated to the study of polymeric materials and devices. We sponsor well attended monthly polymer forums, and annual symposiums or short-courses. The GGPF attracts scientists, engineers, and sales professionals (from start-ups to Fortune 100 companies), as well as academics, all of whom are interested in the study of and advancements in polymer science, materials, or engineering. GGPF events, in addition to providing a forum for cutting edge research and industry practices, allow for collaborative networking. The majority of our attendees are from the Bay Area, yet we attract people from out of state as well as international guests, thanks to our reputation in the industry as a premier and easily affordable educational forum.