Think Big Then Shrink: Micro & Nano Tools for Biomedical Applications
Prof. Michelle Khine
Associate Professor of Biomedical Engineering, Mechanical Engineering, Chemical Engineering and Materials Science
University of California, Irvine
The challenge of micro- and nano-fabrication lies in the difficulties and costs associated with patterning at such high resolution. Instead of relying on traditional fabrication techniques largely inherited from the semiconductor industry we have developed a radically different approach. We pattern at the large scale, which is easy and inexpensive, and rely on the heat-induced relaxation of pre-stressed polymer sheets - commodity shrink-wrap film - to achieve our desired structures. Using this approach, we have demonstrated that we can create fully functional and complete microfluidic devices with integrated nanostructures, printed electronics, and even optical components, all within minutes. These devices can be created for only pennies per chip and without any dedicated costly equipment. Because this process is compatible with roll-to-roll plastic processing, it is also scalable and cost-effective enough for point of care applications.
Michelle Khine is currently an Associate Professor of Biomedical Engineering, Mechanical Engineering, Chemical Engineering and Materials Science at UC Irvine and scientific founder of Shrink Nanotechnologies. She was an Assistant & Founding Professor at UC Merced ('06-'09). Michelle received her BS and MS from UC Berkeley in Mechanical Engineering ('99 and '01, respectively) and her PhD under Luke P. Lee in Bioengineering ('05) from UC Berkeley and UCSF. She co-founded Fluxion Biosciences (South San Francisco) while in graduate school. Michelle was the recipient of the TR35 Award and named one of Forbes '10 Revolutionaries' in 2009, by Fast Company Magazine as one of the '100 Most Creative People in Business' in 2011, and by Marie-Claire Magazine for 'Women on Top: Top Scientist' in 2011. Most recently, she was awarded the NIH New Innovator's Award and was named a finalist in the World Technology Awards for Materials.
6 PM social hour
7 PM dinner
8 PM lecture