Pre-Clinical and Clinical Experience with Biodegradable Polyurethane Foam Occlusion Devices (Landon Nash, Shape Memory Medical)
Pre-Clinical and Clinical Experience with Biodegradable Polyurethane Foam Occlusion Devices
Shape Memory Medical
Shape Memory Medical is a medical device startup located in Santa Clara that is commercializing a porous shape memory polyurethane (SMP) technology initially developed at Lawrence Livermore National Lab and Texas A&M University. These bi-stable materials can be delivered minimally invasively (via a catheter) in a compressed, programmed form factor, for low friction delivery into blood vessels. Once deployed into the target anatomy, the shape memory effect causes the material to passively expand in the aqueous body temperature environment and conform to the vessel site for high volumetric filling. Acutely, the expanded porous foam structure causes the blood to slow down, and the high surface area foreign body material promotes rapid targeted clot formation. Chronically, the foam serves as a tissue scaffold to promote clot remodeling into healed tissue. As healing progresses, the material biodegrades and is replaced with native scar tissue. These unique material properties are being implemented in several commercial products for neurovascular vessel occlusion (aneurysms, fistulas, AVMS) and peripheral vessel occlusion (abdominal aneurysms, pelvic venous congestion, etc.). This seminar will outline the core technology principles, polymer degradation mechanisms, commercialization story, and pre-clinical/clinical implementation of SMP products.
Landon Nash received his PhD from Texas A&M University for developing X-ray visible shape memory polymers and novel plasma surface modifications for medical applications. He has worked as an engineer for Shape Memory Medical since 2013. As an R&D Manager, he oversees neurovascular embolization product development, supports clinical cases, and manages the company’s intellectual property portfolio. He currently serves as Vice President of the Board of Directors for the Surfaces in Biomaterials Foundation.
Wednesday, March 4, 2020
Michael’s at Shoreline
2960 N Shoreline Blvd
Mountain View, CA
6 PM social hour
7 PM dinner
8 PM lecture
Employed/postdoc Student/unemployed/retired Early Registration $30 $15 Registration $35 $20 Walk-in (not guaranteed) $40 $25
Lecture-only is free.
We accept cash or checks at the door, or online payment via credit card. No-shows are responsible for full payment of registration fee.
Please register below or contact:
Deadline for registration:
End of advanced registration: Sunday, February 23, 11:59 PM
End of regular registration: Sunday, March 1, 5:00 PM
Seafood - Broiled Salmon with lemon beurre blanc
Chicken - Breast of Chicken with Marsala
Vegetarian - Mushroom Crepes
You should receive confirmation of your registration; if not, please contact us again.