Events
Healing Broken Hearts : Cardiovascular Implants (S. Venkatraman - UC San Diego and iHealthTech)
Description:
Webinar
Healing Broken Hearts : Cardiovascular Implants
Subbu Venkatraman, Ph.D
Office of Innovation & Commercialization, UC San Diego
Principal Investigator, iHealthTech, Singapore
Wednesday, July 24, Webinar at 5:00 PM Pacific time
Abstract
Major cardiovascular disease manifests in clogged arteries or in defects within the heart. Implants are used for both opening up and closing cardiovascular vessels or defects. A stent is used for reopening clogged arteries, while an occluder is employed for patching up a defect or hole. Historically, such implants have been made of biostable materials (metal or metal-plastic combinations). However, starting in the early 2000’s, there was a push to replace biostable implants with fully or partially degradable ones for reasons that I will cover in my talk.
Although there were attempts to use biodegradable metals for coronary stents, polymers became the material of choice. In our laboratory, we developed fully-resorbable stents for ureteric, tracheal, and peripheral vasculature/ coronary artery applications.
Our experience with the resorbable stent led to other cardiovascular applications such as closure of atrial septal defects (ASD) or patent foramen ovale (PFO). Closure of these defects using permanent occluders (mainly Nitinol-based) leads to long-term complications such as arythmias and thromboembolism, and highlights the need for a biodegradable occluder.
This talk will focus on the design and application of biodegradable cardiovascular implants, using fully-degradable polymers.
Speaker Background
Professor Subbu Venkatraman has a PhD in Polymer Chemistry from Carnegie-Mellon University. He spent about 15 years in biomedical R&D in the USA, working with various applications of medical devices as Product Manager, before joining the Nanyang Technological University, Singapore, as an Associate Professor in 2000. He was instrumental in starting the Biomaterials effort in NTU and developing the paradigm of research driven by medical needs. He served as Associate Chair for Research for 6 years, before taking over as Chair in 2011. Under his watch the School jumped 41 places in the rankings to #3 as per the QS rankings, and #1 as per the US News & World Report rankings.
He has published extensively in the field of biomaterials, with a total of 250 publications, H-index of over 60 and a citation count of over 12,000 He also holds 72 granted patents from a total of 171 applications. He has received the 2014 Singapore President's Technology Award together with Prof Freddy Boey and Adjunct A/P Tina Wong, for their innovative application of nanostructures and novel drug delivery approach to combat blindness from glaucoma.
He is currently in the Office of Innovation & Commericalization at UC San Diego, and maintains an Adjunct Professor appointment at the School of Materials Science & Engineering in both NUS (National University of Singapore) and NTU. His research group is interested in designing and modifying materials for biomedical applications. In this work, they are closely associated with local hospitals and researchers, including the National Heart Centre, NUH, Duke-NUS and the National Cancer Centre. Overall, the focus of the work is in bringing benefits to patients through imaginative use of biomaterials and medical devices.
DATE: Wednesday, July 24
Registration deadline: Tuesday, July 23, 1:00 PM.
Registration may close earlier than the nominal deadline if capacity is reached.
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Webinar Timing: 5:00 PM.
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